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Chair for Bioinorganic Chemistry


clever2_400Prof. Dr. Guido Clever


Technische Universität Dortmund
Anorganische Chemie

Otto-Hahn-Str. 6
D-44227 Dortmund

Room: C1-05-734

Phone: +49 231 755 8677
Fax: +49 231 755 8138


Information for Applicants


Birgit Thormann

Room: C1-05-733
Phone: +49 231 755 4624






(twitter account of the Clever Lab here)

May 2020 


Part of our JSPS-funded collaboration with the group of Keisuke Umakoshi, Nagasaki University, Japan, has just been accepted for publication: S. Horiuchi, C. Matsuo, E. Sakuda, Y. Arikawa, G. H. Clever, K. Umakoshi, Dalton. Trans. 2020, 49, 8472. (HOT article).



March 2020


Congratulations to Irene Regeni for being selected to attend this year's 70th Lindau Nobel Laureate Meeting! In her PhD thesis, Irene works on dye-functionalized coordination cages and their application to DNA secondary structure recognition.


December 2019


The Clever Lab wishes Merry Chistmas!!!



A brand-new JASCO CPL300 is now installed in our Lab, the first one in Germany! It enables us to measure Circularly Polarized Luminescence (CPL) of chiral compounds, cages and so on. The new machine is funded within the RESOLV Cluster of Excellence.

November 2019


And again we are proud to welcome three new group members who will strenthen the Clever Lab: Dr. Pedro Montes Tolentino, postdoc from Mexico (left) and our new PhD students Hannah Kuckling and Simon Kotnig.


October 2019


We are happy to welcome three new members in the Clever Lab: PhD student Shota Hasegawa from Japan and our bachelor students Rameeya Muraleetharan and Marie Langenberg. We are looking forward to work with you!


August 2019


Congratulations to our PhD student Lukas Stratmann who was awarded a poster prize at the ICBIC19 in Interlaken, Switzerland, the biggest international conference on bioinorganic chemistry. He presented his project on EPR-based intermolecular distance measurements in higher-order DNA G-quadruplex structures which he is working on in collaboration with the group of JProf. Kasanmascheff from Physical Chemistry.


July 2019


See this recent highlight of the Clever Lab research activities in self-assembly and fullerene binding in the UniZet magazine (in German).

June 2019


Our PhD student Bin Chen won a IUPAC poster prize at ISMSC 2019 in Lecce, Italy, for his work on fullerene binding bowls recently published in JACS.

The Clever Lab congratulates!


May 2019


Wie macht sich die Natur Übergangsmetall-Kationen zu Nutze? Welche Relevanz haben Selten Erdmetalle wie Europium und Gadolinium in biologischen Markierungsexperimenten und der medizinischen Bildgebung? Welche spannende Chemie kann in künstlichen Nanokäfigen auf Basis von Galliumkomplexen durchgeführt werden?

Hierzu konnte US Chemiker Ken Raymond in den letzten zwei Wochen als erster “Mercator Fellow” des GRK2376, in welchem sich Wissenschaftler von Ruhr-Uni Bochum und TU Dortmund mit chemischen Reaktionen in nanometergroßen Hohlräumen und Kompartimenten beschäftigen, spannende Antworten liefern.   Mehr hier.




March 2019


Congratulations to PhD student Philip Punt who was awarded with the poster prize at the RESOLV Klausurtagung 2019 in Harsewinkel-Marienfeld for his work on “Imidazole-modified metal-binding DNA G-quadruplexes – a step towards artificial metalloenzymes”. In his work he could show how the introduction of imidazole residues in DNA G-quadruplexes leads to tunable metal-binding G-quadruplexes that are able to catalyze various reactions including Michael additions as well as Diels-Alder reactions.


February 2019


Congratulations to PhD student Irene Regeni who was awarded with a poster prize at SupraChem 2019 in Würzburg. Her work on dye-based coordination cages was awarded in the category "Molecular Cages, Switches and Machines" and the prize offered from Springer was presented by Prof. Dr. Markus Albrecht, Editor of J. Incl. Phenom. Macrocycl. Chem.



We regularly conduct diffraction experiments at biomolecular synchrotron beamline P11@DESY for structure elucidation of large metallo-supramolecular assemblies. Two publications in Angew. Chem. on a new M8L16 catenane and cage-in-ring pseudo rotaxane were chosen as science highlight in the 2018 DESY annual report (p. 32 - 33)

December 2018


We congratulate Irene Regeni who was awarded a poster prize on the Supe@Lyon 2018, a popular international symposium on supramolecular chemistry. She presented her interesting work with the title "Self-assembled [Pd2L4] coordination cages based on well-known organic dyes." The prize was handed over by Nobel laureate Sir Fraser Stoddart!



We are happy to welcome two new members in the Clever Lab: Dr. Sudhakar Ganta, postdoc coming from the IIT in Madras, India and our guest scientist Assoc.-Prof. Dr. Eri Sakuda from Nagasaki University in Japan.
Both will work on functional coordination cages.


November 2018


Congratulations to Irene, Soham and Bo for winning the presentation prizes on the first edition of the International Clever Lab Conference!


October 2018


The Clever Lab goes social!

Find our hottest news now also on Twitter.


September 2018


Great news for RESOLV: The joint proposal by RUB and TU Dortmund University was selected by the DFG and the Cluster of Excellence in solvation science will be funded in Germany’s Excellence Strategy for the next seven years.



We happily announce that our recent paper on interpentrated peanut-shaped cages made it on the Front Cover of Angew. Chem.!


n2018-09cWe welcome our two new lab members from the south of China: Qianqian Yan, PhD student coming with a CSC scholarship from Fuzhou University (right) and Dr. Kai Wu, postdoc coming from Sun Yat-Sen University (left). Both will work on functional coordination cages.



For this years scientific retreat, the Clever Lab crossed the north see to visit the island of Juist: Great landscapes, intense seminars and a lot of fun!



We are happy to announce that Haeri Lee from Korea starts her postdoc in the Clever Lab. Her expertise is X-ray crystallography and she will work on functionalized coordination cages.


July 2018


The Clever Lab welcomes new postdoc Jacopo Tessarolo from Italy who will work on functionalized cages.


Together with groups from the RUB Bochum, the Clever Lab is part of the new DFG-funded graduate school GRK 2376 "Confinement-controlled Chemistry" which starts from the 1st of July.



June 2018


Our recent publication "Catenation and Aggregation of Multi-Cavity Coordination Cages" (Angew. Chem. Int. Ed.) was highlighted by Dr. Emiliano Feresin with a short article on the website of the RESOLV cluster of excellence.


May 2018


Dr. Sonja Pullen started her project entitled „Metal Organic Cages for Catalysis Applications” (short „MOCCA“) that is funded by the European Union within the framework of Marie Sklodowska-Curie actions (MSCA). She will work on functional heteroleptic coordination cages for CO2 reduction.


March 2018


The Clever Lab congratulates Philip Punt for winning a poster prize at the RESOLV retreat 2018. On his poster with the title “Imidazole-modified metal-binding DNA G-quadruplexes - a step towards artificial metalloenzymes” he showed how to create designed coordination environments for metal ions on top of G-quadruplex structures.



Our recent publication "Hierarchical Assembly of an Interlocked M8L16 Container" (Angew. Chem. Int. Ed.) was highlighted on the website of the RESOLV cluster of excellence. In a short interview, Guido Clever explains the significance of his new discovery described in this paper.


February 2018

We are excited to announce that our application for the second funding period of the joint project with Prof. Dr. Ricardo Mata, University of Göttingen, within the DFG priority program on Dispersion Interactions (SPP 1807) was successful.


January 2018


The Clever Lab is looking forward to start collecting diffraction data for crystal structure elucidations on its new Bruker D8 Venture single crystal X-ray diffractometer.


We happily acknowledge that our research activities aimed at understanding the formation of monomeric and dimeric palladium cages with banana-shaped ligands have recently received follow-up funding from the DFG.



We welcome our guest scientists Assist.-Prof. Dr. Shinnosuke Horiuchi and Assist.-Prof. Dr. Hironobu Tahara, both from the University of Nagasaki, Japan, in our group.


November 2017

n2017-11The Clever Lab is looking forward to start its measurements on the new Bruker AV 500 Avance NEO NMR spectrometer.


September 2017

 n2017-09bWe are excited to start the operation of our new Bruker timsTOF ion mobility mass spectrometer.


 n2017-09The Clever Lab congratulates Irene Regeni for obtaining a PhD scholarship from the German Fonds of the Chemical Industry (FCI Kekulé stipend) to support her work on dye-functionalized coordination cages.


July 2017

n2017-07We congratulate Marcel Krick who was awarded a poster prize on the ISMSC 2017 in Cambridge, the biggest international symposium on supramolecular chemistry. He presented his work with the title “Endohedral Dynamics of Push-Pull Rotor-Functionalized Cages.“


April 2016

n2016-04Susanne Löffler won the Young Researcher Award 2016 at the 7th Münster Symposium on Cooperative Effects in Chemistry (MSCEC) for her outstanding publication (JACS 2015, 137, 1060) exhibiting the control of host guest chemistry in supramolecular coordination cages. The Clever Lab congratulates!





Sub content

Funding & Projects


ERC Consolidator Grant RAMSES



EXC 2033





GRK 2376


Confinement Controlled Chemistry


SPP 1807

SPP 1807

Control of London dispersion interactions in molecular chemistry


DFG CL489/2-2


Interpenetrated Coordination Cages 


Past Projects


EXC 1069




IRTG 1422

IRTG 1422

Metal Sides in Biomolecules


SFB 1703

SFB 1073

Atomic scale of energy conversion




Catalysis for Sustainable Synthesis